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Context Info
Confidence 0.22
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.82

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pigmentation (MC1R) extracellular space (EDN1) extracellular region (EDN1)
plasma membrane (MC1R) signal transducer activity (MC1R) cell-cell signaling (EDN1)
Anatomy Link Frequency
EDN1 (Homo sapiens)
MC1R (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 12 100.00 Very High Very High Very High
Kinase C 1 87.28 High High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Endothelin-1 increased MC1R mRNA level in NHM regardless of their melanin content.
Endothelin-1 Positive_regulation (increased) of Transcription (level) of MC1R mRNA in NHM associated with melanocortin 1 receptor
1) Confidence 0.22 Published 2002 Journal Pigment Cell Res. Section Abstract Doc Link 12453185 Disease Relevance 0 Pain Relevance 0.82

General Comments

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