INT106976

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Context Info
Confidence 0.52
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.93
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (Asl) aging (Asl) endoplasmic reticulum (Asl)
nucleus (Asl) cellular amino acid metabolic process (Asl) cytoplasm (Asl)
Asl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cerebral cortex 6 91.48 High High
nMDA receptor 3 72.00 Quite High
Glutamate 24 70.04 Quite High
tolerance 3 68.72 Quite High
backache 2 50.00 Quite Low
corticosteroid 35 16.12 Low Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Glutamate receptor 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 63 96.96 Very High Very High Very High
Neurological Disease 3 75.84 Quite High
Stress 10 75.00 Quite High
Low Back Pain 2 50.00 Quite Low
Death 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Exsanguination 2 5.00 Very Low Very Low Very Low
Insulin Resistance 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: It is not likely that efforts to increase the use of ASL will result in measurable economic benefits or improved health outcomes at the population level.
Positive_regulation (increase) of ASL
1) Confidence 0.52 Published 2002 Journal Spine Section Body Doc Link 12461401 Disease Relevance 0 Pain Relevance 0
The increased activities of argininosuccinate synthetase and argininosuccinate lyase suggest the increased and effective recycling of citrulline to arginine in anoxia, making nitric oxide production more effective and contributing to its toxic effects.
Positive_regulation (increased) of argininosuccinate lyase associated with hypoxia
2) Confidence 0.45 Published 2010 Journal International Journal of Medical Sciences Section Abstract Doc Link PMC2880843 Disease Relevance 0.93 Pain Relevance 0.12
OBJECTIVE: To evaluate the effects of two strategies to increase the use of active sick leave (ASL) among patients with low back pain (LBP) on improved return to work and quality of life.
Positive_regulation (increase) of ASL
3) Confidence 0.35 Published 2002 Journal Spine Section Body Doc Link 12461401 Disease Relevance 0 Pain Relevance 0
The biphasic pattern is more apparent for ornithine decarboxylase (ODC) and CCAAT/enhancer binding protein (CEBP-?)
Positive_regulation (apparent) of ASL
4) Confidence 0.32 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733100 Disease Relevance 0 Pain Relevance 0.03

General Comments

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