INT107322

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.13
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.64
Pain Relevance 2.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (TRPV1) intracellular (IL8) lipid metabolic process (TRPV1)
cytosol (TRPV1) extracellular space (IL8) signal transduction (IL8)
Anatomy Link Frequency
keratinocytes 3
TRPV1 (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 17 100.00 Very High Very High Very High
antagonist 3 93.08 High High
bradykinin 50 91.56 High High
Eae 14 86.56 High High
cytokine 5 84.20 Quite High
Pain 32 82.88 Quite High
Inflammation 22 82.24 Quite High
Osteoarthritis 3 79.84 Quite High
rheumatoid arthritis 3 77.92 Quite High
agonist 4 73.12 Quite High
Disease Link Frequency Relevance Heat
Inflammatory Pain 13 86.56 High High
Pain 34 82.88 Quite High
INFLAMMATION 27 82.24 Quite High
Osteoarthritis 3 79.84 Quite High
Rheumatoid Arthritis 3 77.92 Quite High
Injury 36 52.80 Quite High
Hyperalgesia 2 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of the TRPV1 results in an increased release of IL-8 and PGE2 by epidermal keratinocytes [49], IL-6 [53] and IL-8 [54] by human bronchial epithelial cells and IL-6 by dental pulp fibroblast [52].
Positive_regulation (Activation) of TRPV1 in keratinocytes Positive_regulation (results) of Localization (release) of IL-8 in keratinocytes
1) Confidence 0.13 Published 2010 Journal Mol Pain Section Body Doc Link PMC2834653 Disease Relevance 0.76 Pain Relevance 0.85
Activation of the epidermal VR1 by capsaicin also resulted in an increased release of interleukin-8 and prostaglandin E2, and the stimulated release was attenuated by capsazepine.
Positive_regulation (Activation) of VR1 Positive_regulation (resulted) of Localization (release) of interleukin-8 associated with qutenza
2) Confidence 0.12 Published 2003 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12490594 Disease Relevance 0.44 Pain Relevance 0.83
Activation of the epidermal VR1 by capsaicin also resulted in an increased release of interleukin-8 and prostaglandin E2, and the stimulated release was attenuated by capsazepine.
Positive_regulation (Activation) of VR1 Positive_regulation (increased) of Localization (release) of interleukin-8 associated with qutenza
3) Confidence 0.12 Published 2003 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12490594 Disease Relevance 0.44 Pain Relevance 0.83

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox