INT107331

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Context Info
Confidence 0.01
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 3.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Adarb1) intracellular (Adarb1) extracellular space (PPBP)
extracellular region (PPBP) RNA binding (Adarb1) nucleolus (Adarb1)
PPBP (Homo sapiens)
Adarb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 27 100.00 Very High Very High Very High
Immobilon 12 100.00 Very High Very High Very High
opioid receptor 9 100.00 Very High Very High Very High
Morphine 6 100.00 Very High Very High Very High
agonist 18 99.36 Very High Very High Very High
Antinociceptive 12 98.20 Very High Very High Very High
Enkephalin 3 93.08 High High
Buprenorphine 3 88.80 High High
withdrawal 3 85.68 High High
MU agonist 3 79.60 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
High doses of CTAP produced a noncompetitive antagonism of etorphine s.c. and morphine s.c. suggesting that CTAP may interact with additional opioid receptors in vivo or produce insurmountable antagonism at these doses.
CTAP Binding (interact) of receptors associated with opioid receptor, morphine and immobilon
1) Confidence 0.01 Published 2003 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12490605 Disease Relevance 0 Pain Relevance 1.49
D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP) is a peptide antagonist that demonstrates potent and selective affinity for micro-opioid receptors in radioligand binding assays and in vitro bioassays.
CTAP Binding (affinity) of receptors associated with antagonist and opioid receptor
2) Confidence 0.00 Published 2003 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12490605 Disease Relevance 0 Pain Relevance 0.65
High doses of CTAP produced a noncompetitive antagonism of etorphine s.c. and morphine s.c. suggesting that CTAP may interact with additional opioid receptors in vivo or produce insurmountable antagonism at these doses.
CTAP Binding (interact) of receptors associated with opioid receptor, morphine and immobilon
3) Confidence 0.00 Published 2003 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12490605 Disease Relevance 0 Pain Relevance 1.52

General Comments

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