INT107400

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Context Info
Confidence 0.28
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.95
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
Articular 1
blood 1
B-cell 1
Das (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 1 94.48 High High
qutenza 8 94.04 High High
Inflammation 27 93.20 High High
cytokine 8 87.56 High High
rheumatoid arthritis 95 85.88 High High
antagonist 3 75.00 Quite High
cINOD 4 57.24 Quite High
Pain 8 53.92 Quite High
Inflammatory marker 2 52.08 Quite High
Infliximab 108 50.00 Quite Low
Disease Link Frequency Relevance Heat
Inflammatory Bowel Disease 106 100.00 Very High Very High Very High
Pressure And Volume Under Development 3 98.88 Very High Very High Very High
INFLAMMATION 27 93.20 High High
Disease 161 91.84 High High
Rheumatoid Arthritis 99 85.88 High High
Arthritis 9 77.60 Quite High
Pain 4 53.92 Quite High
Colon Cancer 3 44.80 Quite Low
Hemorrhage 4 43.88 Quite Low
Toxic Megacolon 2 42.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we examined the effect of lafutidine on gastric mucosal blood flow (GMBF) and duodenal HCO3- secretion (DAS) under basal and acid-stimulated conditions in rats.
Localization (secretion) of DAS in blood
1) Confidence 0.28 Published 2002 Journal Dig. Dis. Sci. Section Abstract Doc Link 12498288 Disease Relevance 0 Pain Relevance 0.30
The DAS was calculated using a 44 joint count for swelling (swollen joint count, SJC), a 53 joint count graded for tenderness (tender joint count, TJC), counted in 26 joint units (Ritchie Articular Index, RAI), general health on a Visual Analogue Scale (VAS) of 100 mm, and the value for ESR measured by the Westergren method[16].
Localization (calculated) of DAS in Articular associated with pressure and volume under development
2) Confidence 0.12 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911884 Disease Relevance 0.75 Pain Relevance 0.21
An advantage of the SDAI and CDAI over the DAS is that they do not require a complex formula or a calculator and can be used more readily in clinical practice.
Localization (advantage) of DAS
3) Confidence 0.07 Published 2010 Journal Curr Rheumatol Rep Section Body Doc Link PMC2927687 Disease Relevance 0.74 Pain Relevance 0.14
Also, autoantibodies directed against endogenous proteins such as tropomyosins are secreted in the serum of UC patients, corroborating the role of humoral, B-cell-mediated immunity in UC (Das et al. 1993).
Localization (secreted) of Das in B-cell associated with inflammatory bowel disease
4) Confidence 0.03 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012439 Disease Relevance 1.46 Pain Relevance 0.34

General Comments

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