INT107474

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Context Info
Confidence 0.61
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Mc1r) signal transduction (Mc1r) plasma membrane (Mc1r)
signal transducer activity (Mc1r)
Mc1r (Mus musculus)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 11 100.00 Very High Very High Very High
agonist 2 90.92 High High
Disease Link Frequency Relevance Heat
Cancer 2 96.40 Very High Very High Very High
Skin Cancer 4 81.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In B 16F1 cells, a single injection of 50 to 500 microg alpha-MSH induced a rapid but moderate dose-dependent MC1R down-regulation which could be totally reverted within 16-24 h.
Positive_regulation (induced) of Negative_regulation (down-regulation) of MC1R associated with melanocortin 1 receptor
1) Confidence 0.61 Published 2002 Journal J. Recept. Signal Transduct. Res. Section Abstract Doc Link 12503610 Disease Relevance 0.41 Pain Relevance 0.89

General Comments

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