INT107502

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.59
First Reported 2002
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.18
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

methyltransferase activity (Gamt)
Gamt (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 18 97.70 Very High Very High Very High
Parenteral administration 2 97.36 Very High Very High Very High
agonist 4 93.84 High High
gABA 10 75.00 Quite High
anesthesia 8 69.28 Quite High
isoflurane 8 54.96 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 18 99.36 Very High Very High Very High
Disease 4 93.76 High High
Convulsion 2 85.36 High High
Dyskinesias 2 84.32 Quite High
Aging 14 66.32 Quite High
Hypertrophy 8 65.08 Quite High
Body Weight 24 60.96 Quite High
Stroke 6 60.48 Quite High
Coronary Heart Disease 2 54.04 Quite High
Death 2 43.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Guanidinoacetate methyltransferase (GAMT) deficiency is an autosomal recessively inherited disorder of creatine biosynthesis.
Negative_regulation (deficiency) of Guanidinoacetate methyltransferase
1) Confidence 0.59 Published 2002 Journal Neurobiol. Dis. Section Abstract Doc Link 12505422 Disease Relevance 0.33 Pain Relevance 0.04
Guanidinoacetate methyltransferase (GAMT) deficiency is an autosomal recessively inherited disorder of creatine biosynthesis.
Negative_regulation (deficiency) of GAMT
2) Confidence 0.59 Published 2002 Journal Neurobiol. Dis. Section Abstract Doc Link 12505422 Disease Relevance 0.33 Pain Relevance 0.04
We have used high-resolution cine-MRI to systematically assess cardiac function in a transgenic, creatine free, mouse model of GAMT deficiency [7,8,18].
Negative_regulation (deficiency) of GAMT associated with targeted disruption
3) Confidence 0.41 Published 2008 Journal J Cardiovasc Magn Reson Section Body Doc Link PMC2254407 Disease Relevance 0.21 Pain Relevance 0.03
One limitation of this study is that, in order to keep the protocol as non-invasive as possible and to avoid loss of animals during the imaging procedure, we did not make acute measurements of cardiac functional reserve, which we have previously shown to be impaired in GAMT ko mice [12].
Negative_regulation (impaired) of GAMT associated with imagery
4) Confidence 0.36 Published 2008 Journal J Cardiovasc Magn Reson Section Body Doc Link PMC2254407 Disease Relevance 0.31 Pain Relevance 0.33

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox