INT107552

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Context Info
Confidence 0.37
First Reported 2002
Last Reported 2005
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.48
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Marcks) cytoplasm (Marcks)
Anatomy Link Frequency
LGN 1
Marcks (Rattus norvegicus)
Pain Link Frequency Relevance Heat
gABA 2 99.14 Very High Very High Very High
Inflammation 3 94.40 High High
Neuropathic pain 4 93.72 High High
Neurotransmitter 1 89.28 High High
Kinase C 4 83.20 Quite High
Pain 3 73.04 Quite High
intrathecal 1 62.72 Quite High
tetrodotoxin 1 51.68 Quite High
Spinal cord 3 50.56 Quite High
Neuronal nitric oxide synthase 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 94.40 High High
Neuropathic Pain 4 93.72 High High
Pain 1 73.04 Quite High
Inflammatory Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GABA-immunoreactive neurons in the LGN did not contain MARCKS mRNA, indicating that MARCKS mRNA is not expressed in inhibitory interneurons.
Neg (not) Regulation (contain) of MARCKS in LGN associated with gaba
1) Confidence 0.37 Published 2002 Journal Vis. Neurosci. Section Abstract Doc Link 12507329 Disease Relevance 0 Pain Relevance 0.26
Since the function of MARCKS is regulated by phosphorylation at multiple sites, here we examined the involvement of Rho-kinase in relation to phosphorylation of MARCKS at Ser159 in inflammatory and neuropathic pain by H-1152.
Regulation (regulated) of MARCKS associated with inflammation and neuropathic pain
2) Confidence 0.30 Published 2005 Journal Neuroscience Section Abstract Doc Link 15708490 Disease Relevance 0.48 Pain Relevance 0.54

General Comments

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