INT107608

Context Info Confidence 0.17 First Reported 2002 Last Reported 2002 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.40 Pain Relevance 0.34

cytoplasm (MMP14)

MMP14 (Homo sapiens)

Pain Link Frequency Relevance Heat metalloproteinase 1 100.00 Adalimumab 4 99.10 methotrexate 2 87.84 Pain 1 74.84

Disease Link Frequency Relevance Heat Rheumatoid Arthritis 3 98.40 Necrosis 1 70.24 Cancer 1 69.88

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In adalimumab recipient, radiographic progression is also controlled and serum levels of matrix metalloproteinase-1(MMP-1) and MMP-3 decrease.

Regulation (controlled) of Negative_regulation (decrease) of matrix metalloproteinase-1 associated with metalloproteinase and adalimumab

1) Confidence 0.17 Published 2002 Journal Nippon Rinsho Section Abstract Doc Link 12510366 Disease Relevance 0.40 Pain Relevance 0.34

General Comments

This test has worked.