INT107611

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Context Info
Confidence 0.42
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.89
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Notch3) plasma membrane (Notch3) nucleus (Notch3)
Anatomy Link Frequency
Notch 1
Notch3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Migraine 1 98.28 Very High Very High Very High
Substantia nigra 7 83.00 Quite High
ketamine 3 66.72 Quite High
agonist 1 56.44 Quite High
dopamine receptor 1 56.12 Quite High
anesthesia 1 31.28 Quite Low
Dopamine 10 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Ventral tegmentum 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 1 98.28 Very High Very High Very High
Disease 43 97.76 Very High Very High Very High
Dementia 1 96.68 Very High Very High Very High
Stroke 5 95.80 Very High Very High Very High
Cadasil 2 93.20 High High
Leukoencephalopathies 1 92.84 High High
Leukoaraiosis 2 75.00 Quite High
Neurodegenerative Disease 9 5.00 Very Low Very Low Very Low
Parkinson's Disease 8 5.00 Very Low Very Low Very Low
INFLAMMATION 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mutations in the Notch3 gene are responsible.
Regulation (responsible) of Notch3
1) Confidence 0.42 Published 2003 Journal Stroke Section Abstract Doc Link 12511775 Disease Relevance 0.89 Pain Relevance 0.10
Ten-micron-thick tissue sections were stained to visualize the cells that were positive for TH, ubiquitin, Notch-3, IBA-1, GFAP and iNOS, according to a previously described immunohistochemical procedure [40].
Regulation (positive) of Notch-3 in Notch
2) Confidence 0.24 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC3000094 Disease Relevance 0 Pain Relevance 0.13

General Comments

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