INT107615

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Context Info
Confidence 0.55
First Reported 2002
Last Reported 2007
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.05
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL1B, PTGES) isomerase activity (PTGES) aging (IL1B)
cytoplasm (PTGES) cell-cell signaling (IL1B) cytosol (IL1B)
Anatomy Link Frequency
HMSM 1
umbilical vein 1
IL1B (Homo sapiens)
PTGES (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 3 100.00 Very High Very High Very High
Paracetamol 1 54.28 Quite High
antagonist 1 54.28 Quite High
dexamethasone 1 53.56 Quite High
cINOD 2 52.24 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 1 51.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-1beta stimulated release of PGE(2) by HMSM cells and increased COX-2 and mPGES-1 mRNA and protein expression.
IL-1beta Positive_regulation (increased) of mPGES-1 mRNA in HMSM
1) Confidence 0.55 Published 2007 Journal Mol. Hum. Reprod. Section Abstract Doc Link 17105783 Disease Relevance 0.05 Pain Relevance 0.13
Interleukin 1beta induces functional prostaglandin E synthase in cultured human umbilical vein endothelial cells.
Interleukin 1beta Positive_regulation (induces) of E synthase in umbilical vein associated with cox2
2) Confidence 0.09 Published 2002 Journal J. Physiol. Pharmacol. Section Title Doc Link 12512699 Disease Relevance 0 Pain Relevance 0.13

General Comments

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