INT107616

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Context Info
Confidence 0.37
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (PTGER3) aging (IL1B) signal transducer activity (PTGER3)
cell-cell signaling (IL1B) cytosol (IL1B) extracellular space (IL1B)
Anatomy Link Frequency
umbilical vein 2
IL1B (Homo sapiens)
PTGER3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 3 94.80 High High
dexamethasone 3 93.36 High High
COX2 3 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we demonstrated that interleukin 1beta (IL-1beta) is an inducer of COX-2 and PGE-S in human umbilical vein endothelial cells (HUVEC).
interleukin 1beta Positive_regulation (inducer) of PGE-S in umbilical vein
1) Confidence 0.37 Published 2002 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 12512699 Disease Relevance 0 Pain Relevance 0.10
Here we demonstrated that interleukin 1beta (IL-1beta) is an inducer of COX-2 and PGE-S in human umbilical vein endothelial cells (HUVEC).
IL-1beta Positive_regulation (inducer) of PGE-S in umbilical vein
2) Confidence 0.26 Published 2002 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 12512699 Disease Relevance 0 Pain Relevance 0.10
Actinomycin D, a classical transcription inhibitor, was used to prove that indeed IL-1beta induced the functional PGE-S enzyme.
IL-1beta Positive_regulation (induced) of PGE-S
3) Confidence 0.24 Published 2002 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 12512699 Disease Relevance 0 Pain Relevance 0.14

General Comments

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