INT107658

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Context Info
Confidence 0.26
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grm5) cytoplasm (Grm5) signal transducer activity (Grm5)
Anatomy Link Frequency
neurons 2
Grm5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 16 99.68 Very High Very High Very High
antagonist 1 98.16 Very High Very High Very High
Arthritis 3 90.88 High High
Pain 8 87.68 High High
parabrachial 3 82.32 Quite High
Glutamate receptor 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Arthritis 9 99.40 Very High Very High Very High
Nociception 1 81.52 Quite High
Pain 5 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A selective mGluR1 antagonist reduced transmission in CeA neurons from arthritic animals but not in control neurons, and increased levels of mGluR1 and mGluR5 protein were measured in the CeA of arthritic rats compared with controls.
Regulation (measured) of Positive_regulation (increased) of mGluR5 protein in neurons associated with antagonist, amygdala and arthritis
1) Confidence 0.26 Published 2003 Journal J. Neurosci. Section Abstract Doc Link 12514201 Disease Relevance 0.84 Pain Relevance 1.17

General Comments

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