INT107694

Context Info Confidence 0.60 First Reported 2002 Last Reported 2002 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.63 Pain Relevance 0.43

extracellular space (Tnf, Cxcl1) extracellular region (Tnf, Cxcl1) signal transduction (Tnf) plasma membrane (Tnf) intracellular (Tnf) extracellular matrix organization (Tnf)

Anatomy Link Frequency skin 2 Tnf (Rattus norvegicus) Cxcl1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Inflammation 3 93.28 Hyperalgesia 2 90.40 antagonist 1 76.84 cytokine 3 75.00 chemokine 3 25.00 nociceptor 2 25.00

Disease Link Frequency Relevance Heat Hypersensitivity 5 97.12 INFLAMMATION 3 75.00 Hyperalgesia 3 66.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In addition, carrageenin, LPS and TNF-alpha were shown to stimulate the production of immunoreactive CINC-1 in the skin of injected paws.

TNF-alpha Positive_regulation (stimulate) of Gene_expression (production) of CINC-1 in skin

1) Confidence 0.60 Published 2002 Journal Eur. Cytokine Netw. Section Abstract Doc Link 12517731 Disease Relevance 0.63 Pain Relevance 0.43

General Comments

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