INT107725

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Context Info
Confidence 0.41
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.06

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pigmentation (ASIP) signal transduction (ASIP) generation of precursor metabolites and energy (ASIP)
extracellular space (ASIP) extracellular region (ASIP) cytoplasm (EVI2B)
ASIP (Homo sapiens)
EVI2B (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 4 64.48 Quite High
Disease Link Frequency Relevance Heat
Skin Cancer 5 84.92 Quite High
Microphthalmia 1 60.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Results identify five genes, namely PPARbeta, eIF-4B, RRM2, MINOR and EVI2B that are down-regulated by ASIP, indicating a likely role for ASIP in human melanogenesis.
ASIP Negative_regulation (down-regulated) of EVI2B
1) Confidence 0.41 Published 2003 Journal Pigment Cell Res. Section Abstract Doc Link 12519127 Disease Relevance 0.43 Pain Relevance 0.06

General Comments

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