INT107727

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Context Info
Confidence 0.29
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RRM2) small molecule metabolic process (RRM2) cytoplasm (RRM2)
cell-cell signaling (ASIP) cytosol (RRM2) pigmentation (ASIP)
ASIP (Homo sapiens)
RRM2 (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 4 65.12 Quite High
Disease Link Frequency Relevance Heat
Skin Cancer 5 85.56 High High
Microphthalmia 1 61.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Results identify five genes, namely PPARbeta, eIF-4B, RRM2, MINOR and EVI2B that are down-regulated by ASIP, indicating a likely role for ASIP in human melanogenesis.
ASIP Negative_regulation (down-regulated) of RRM2
1) Confidence 0.29 Published 2003 Journal Pigment Cell Res. Section Abstract Doc Link 12519127 Disease Relevance 0.43 Pain Relevance 0.07

General Comments

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