INT107746

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Context Info
Confidence 0.39
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (HSD17B1) intracellular (TNF) extracellular matrix organization (TNF)
cytoplasm (HSD17B1) cytosol (HSD17B1) extracellular space (TNF)
TNF (Homo sapiens)
HSD17B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 97.08 Very High Very High Very High
agonist 1 65.92 Quite High
Clonidine 1 57.28 Quite High
Disease Link Frequency Relevance Heat
Obesity 4 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TNF alpha up-regulated 11 beta-HSD-1 activity maximally at 0.6 x 10(-9) M (140 +/- 20%; P < 0.001); the same cytokine increased 11 beta-HSD-1 mRNA levels to 3-fold of control (P < 0.05) and increased medium glycerol levels to 165 +/- 14% of control (P < 0.01).
TNF alpha Positive_regulation (up-regulated) of beta-HSD-1 associated with cytokine
1) Confidence 0.39 Published 2003 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 12519881 Disease Relevance 0.20 Pain Relevance 0.17

General Comments

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