INT107894

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Context Info
Confidence 0.75
First Reported 2003
Last Reported 2010
Negated 2
Speculated 2
Reported most in Body
Documents 5
Total Number 7
Disease Relevance 1.14
Pain Relevance 2.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nfkbib) signal transduction (Nfkbib) nucleus (Nfkbib)
cytoplasm (Nfkbib)
Anatomy Link Frequency
hair 1
B-cells 1
tooth 1
Nfkbib (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 172 98.92 Very High Very High Very High
Inflammation 54 95.04 Very High Very High Very High
qutenza 22 93.68 High High
Opioid 28 73.04 Quite High
tolerance 8 72.16 Quite High
withdrawal 9 64.68 Quite High
adenocard 2 63.32 Quite High
Physical dependence 10 59.40 Quite High
antagonist 12 55.12 Quite High
COX2 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Sprains And Strains 88 98.08 Very High Very High Very High
INFLAMMATION 59 95.04 Very High Very High Very High
Opiate Addiction 8 64.68 Quite High
Drug Dependence 12 59.40 Quite High
Targeted Disruption 2 30.96 Quite Low
Respiratory Failure 1 13.16 Low Low
Hypoxia 2 11.84 Low Low
Periodontitis 30 5.00 Very Low Very Low Very Low
Apoptosis 16 5.00 Very Low Very Low Very Low
Shock 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression levels of COX-2, iNOS, IkB-a, and vanilloid receptor-1 (VR-1) were determined at the protein and mRNA levels.
Spec (determined) Gene_expression (expression) of IkB
1) Confidence 0.75 Published 2003 Journal Cell. Signal. Section Abstract Doc Link 12531428 Disease Relevance 0.35 Pain Relevance 0.85
The levels of IkB-?
Gene_expression (levels) of IkB
2) Confidence 0.65 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC3000377 Disease Relevance 0 Pain Relevance 0
The expression levels of COX-2, iNOS, IkB-a, and vanilloid receptor-1 (VR-1) were determined at the protein and mRNA levels.
Spec (determined) Gene_expression (levels) of IkB
3) Confidence 0.58 Published 2003 Journal Cell. Signal. Section Abstract Doc Link 12531428 Disease Relevance 0.35 Pain Relevance 0.85
There was a tendency for a day × status interaction (P = 0.08), day (P = 0.07) and status (P = 0.09) for NFKBIB gene expression.
Gene_expression (expression) of NFKBIB
4) Confidence 0.24 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2876169 Disease Relevance 0 Pain Relevance 0
However, we found no detectable expression of Edar in the developing palate, nor of IkB (SP, data not shown), which is a feedback transcriptional target of EDAR signaling in both hair and tooth [35,39,40].
Neg (no) Gene_expression (expression) of IkB in hair
5) Confidence 0.16 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2637861 Disease Relevance 0 Pain Relevance 0
Strain differences in response to acute morphine were also detected in the level of nuclear factor of kappa light chain gene enhancer in B-cells inhibitor ?
Gene_expression (enhancer) of kappa light chain gene in B-cells associated with sprains and strains and morphine
6) Confidence 0.08 Published 2007 Journal Genome Biol Section Body Doc Link PMC2394777 Disease Relevance 0.45 Pain Relevance 0.85
However, we found no detectable expression of Edar in the developing palate, nor of IkB (SP, data not shown), which is a feedback transcriptional target of EDAR signaling in both hair and tooth [35,39,40].
Neg (no) Gene_expression (expression) of IkB in tooth
7) Confidence 0.06 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2637861 Disease Relevance 0 Pain Relevance 0

General Comments

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