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Context Info
Confidence 0.33
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mastl) signal transducer activity (Oprm1) signal transduction (Oprm1)
mitosis (Mastl) plasma membrane (Oprm1) nucleus (Mastl)
Oprm1 (Mus musculus)
Mastl (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 3 99.96 Very High Very High Very High
withdrawal 2 98.16 Very High Very High Very High
Antinociceptive 1 87.52 High High
tolerance 3 86.76 High High
antinociception 1 75.04 Quite High
Cannabinoid 4 75.00 Quite High
opioid receptor 2 75.00 Quite High
Physical dependence 1 61.40 Quite High
Opioid 1 57.68 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 6 93.68 High High
Opiate Addiction 1 75.00 Quite High
Drug Dependence 1 61.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, the somatic manifestations of THC withdrawal were also significantly attenuated in mutant mice, suggesting that a cooperative action of MOR and DOR is required for the entire expression of THC dependence.
MOR Positive_regulation (required) of Gene_expression (expression) of THC associated with addiction and withdrawal
1) Confidence 0.33 Published 2003 Journal Eur. J. Neurosci. Section Abstract Doc Link 12534979 Disease Relevance 0.61 Pain Relevance 0.71

General Comments

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