INT107951

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Context Info
Confidence 0.11
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.21
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Pax3) extracellular space (Tac1) extracellular region (Tac1)
plasma membrane (Tac1) nucleus (Pax3) DNA binding (Pax3)
Anatomy Link Frequency
spinal cord 2
Pax3 (Mus musculus)
Tac1 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 8 100.00 Very High Very High Very High
Spinal cord 4 99.24 Very High Very High Very High
Lasting pain 2 88.40 High High
Inflammation 12 81.76 Quite High
Inflammatory stimuli 2 68.72 Quite High
withdrawal 6 66.00 Quite High
Pain 2 25.00 Low Low
nociceptor 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 6 99.88 Very High Very High Very High
Pain 2 87.52 High High
INFLAMMATION 6 81.76 Quite High
Hyperalgesia 4 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The release of SP from primary afferent neurons is increased during nociception, and SP activates neurokinin-1 (NK-1) receptors in the spinal cord and periphery.
SP Positive_regulation (activates) of neurokinin-1 in spinal cord associated with nociception, spinal cord and substance p
1) Confidence 0.11 Published 2003 Journal Brain Res. Section Abstract Doc Link 12535787 Disease Relevance 0.60 Pain Relevance 0.48
The release of SP from primary afferent neurons is increased during nociception, and SP activates neurokinin-1 (NK-1) receptors in the spinal cord and periphery.
SP Positive_regulation (activates) of NK-1 in spinal cord associated with nociception, spinal cord and substance p
2) Confidence 0.09 Published 2003 Journal Brain Res. Section Abstract Doc Link 12535787 Disease Relevance 0.61 Pain Relevance 0.48

General Comments

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