INT107984

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Context Info
Confidence 0.11
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear chromosome (MSH2) ATPase activity (MSH2) nucleus (MSH2)
enzyme binding (MSH2) DNA binding (MSH2)
Anatomy Link Frequency
SW480 2
MSH2 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 10 50.00 Quite Low
cINOD 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 6 50.00 Quite Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Microsatellite Instability 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In HCT116+chr3 cells, treatment with 1 mM of aspirin increased expression of the hMLH1 and hPMS2 proteins by 2.5-fold and 2-fold, respectively, and increased expression of the hMSH2 and hMSH6 proteins by 2-3-fold.
Positive_regulation (increased) of Gene_expression (expression) of hMSH2
1) Confidence 0.11 Published 2003 Journal Clin. Cancer Res. Section Body Doc Link 12538492 Disease Relevance 0 Pain Relevance 0
For SW480 cells, treatment with 1 and 5 mM of aspirin increased expression of the hMLH1 and hPMS2 proteins by 2-4-fold and 3-5-fold, respectively, and increased expression of the hMSH2 and hMSH6 proteins by 3-7-fold.
Positive_regulation (increased) of Gene_expression (expression) of hMSH2 in SW480
2) Confidence 0.11 Published 2003 Journal Clin. Cancer Res. Section Body Doc Link 12538492 Disease Relevance 0 Pain Relevance 0

General Comments

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