INT107988

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Context Info
Confidence 0.40
First Reported 2003
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (MRC1) plasma membrane (MRC1)
Anatomy Link Frequency
colon 1
MRC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 5 50.00 Quite Low
Taxol 1 31.44 Quite Low
alcohol 19 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 1 98.90 Very High Very High Very High
Disease 36 95.40 Very High Very High Very High
Colon Cancer 22 78.00 Quite High
Cancer 26 63.36 Quite High
Reprotox - General 1 7 51.52 Quite High
Leukemia 1 51.00 Quite High
Carcinoma 9 50.00 Quite Low
Communicable Diseases 15 32.48 Quite Low
Chronic Disease 13 30.72 Quite Low
Cleidocranial Dysplasia 1 17.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EXPERIMENTAL DESIGN: In this study, we have examined the effects of aspirin on the cellular growth rates, MMR protein levels, cell cycle analysis and apoptosis in MMR-deficient (HCT116) and MMR-proficient (HCT116+chr3 and SW480) human colon cancer cell lines.
Spec (examined) Regulation (effects) of MMR protein in colon
1) Confidence 0.40 Published 2003 Journal Clin. Cancer Res. Section Body Doc Link 12538492 Disease Relevance 0 Pain Relevance 0
However, unlike familial adenomatous polyposis, very little is known about phenotypic variation as a function of the MMR gene involved or the location and nature of the specific MMR gene mutation.
Regulation (function) of MMR gene associated with familial adenomatous polyposis
2) Confidence 0.14 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2795749 Disease Relevance 0.51 Pain Relevance 0
Major efforts to control and reduce MMR in Cuba include: continued training of maternity personnel; major emphasis to primary health; and creation and expansion of clinics, hospitals, and health centers in the country [62].
Regulation (control) of MMR
3) Confidence 0.10 Published 2010 Journal International Journal of Environmental Research and Public Health Section Body Doc Link PMC2898047 Disease Relevance 0.05 Pain Relevance 0

General Comments

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