INT10801

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Context Info
Confidence 0.73
First Reported 1992
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.12
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (CD36) transport (CD36) small molecule metabolic process (CD36)
cell adhesion (CD36) Golgi apparatus (CD36) plasma membrane (CD36)
Anatomy Link Frequency
macrophages 1
hepatocyte 1
fat 1
CD36 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 77 96.36 Very High Very High Very High
Chronic pancreatitis 3 85.20 High High
metalloproteinase 2 65.84 Quite High
antagonist 4 13.68 Low Low
Inflammation 10 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Bile 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Leukemia 52 94.84 High High
Disease 9 91.64 High High
Stress 8 91.52 High High
Fatty Liver 6 89.92 High High
Rheumatoid Arthritis 4 88.08 High High
Obesity 86 86.80 High High
Myeloid Leukemia 28 85.68 High High
Pancreatitis 3 85.20 High High
Body Weight 2 83.08 Quite High
Steatorrhea 3 79.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
THP-1 cells into macrophages, as shown by the expression of CD36 scavenger
Localization (scavenger) of CD36 in macrophages
1) Confidence 0.73 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408681 Disease Relevance 1.18 Pain Relevance 0.08
There was a highly significant correlation between these values (r = 0.77 p less than 0.0003) and a highly significant inverse correlation between fecal fat and chymotrypsin excretion, both when the latter was measured on random and on previously homogenized samples (p less than 0.0001).
Localization (excretion) of fat in fat
2) Confidence 0.68 Published 1992 Journal Minerva Gastroenterol Dietol Section Abstract Doc Link 1520749 Disease Relevance 0.39 Pain Relevance 0.23
Several PPAR target genes, such as CYP4A1, CPT1, or CD36, were induced in the two hepatocyte cultures treated by 40??
Localization (Several) of CD36 in hepatocyte
3) Confidence 0.37 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 0.09 Pain Relevance 0
Noticeable increase was observed in Cd36, glucokinase (Gk), malic enzyme (Me), low-density lipoprotein (Ldl), microsomal transfer protein (Mtp), and angiopoietin-like 4 (Angptl4) in the absence of any change in CCAAT/enhancer binding protein alpha (C/ebp?)
Localization (observed) of Cd36
4) Confidence 0.37 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 0.46 Pain Relevance 0

General Comments

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