INT108044

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Context Info
Confidence 0.25
First Reported 2002
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.39
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Syk) plasma membrane (Syk) cytoplasm (Syk)
Anatomy Link Frequency
spleen 1
Syk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 12 99.08 Very High Very High Very High
Inflammatory response 2 93.04 High High
Inflammation 3 78.60 Quite High
Angina 2 60.44 Quite High
cINOD 1 43.80 Quite Low
Disease Link Frequency Relevance Heat
Stress 8 100.00 Very High Very High Very High
INFLAMMATION 6 93.04 High High
Acute Coronary Syndrome 2 68.12 Quite High
Cv General 3 Under Development 2 60.44 Quite High
Myocardial Infarction 2 59.64 Quite High
Cardiovascular Disease 2 58.20 Quite High
Thrombosis 2 55.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, Western blotting demonstrated that a 72 kDa protein tentatively identified as Syk became phosphorylated in response to shear stress and that its phosphorylation was inhibited by each antagonist.
Phosphorylation (phosphorylated) of Syk associated with stress and antagonist
1) Confidence 0.25 Published 2002 Journal Ann Biomed Eng Section Abstract Doc Link 12540202 Disease Relevance 0.53 Pain Relevance 0.30
Additionally, Western blotting demonstrated that a 72 kDa protein tentatively identified as Syk became phosphorylated in response to shear stress and that its phosphorylation was inhibited by each antagonist.
Phosphorylation (phosphorylation) of Syk associated with stress and antagonist
2) Confidence 0.25 Published 2002 Journal Ann Biomed Eng Section Abstract Doc Link 12540202 Disease Relevance 0.53 Pain Relevance 0.31
Distinct role of spleen tyrosine kinase in the early phosphorylation of inhibitor of kappaB alpha via activation of the phosphoinositide-3-kinase and Akt pathways.
Phosphorylation (phosphorylation) of spleen tyrosine kinase in spleen
3) Confidence 0.05 Published 2009 Journal Int. J. Biochem. Cell Biol. Section Title Doc Link 18775507 Disease Relevance 0.33 Pain Relevance 0.16

General Comments

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