INT108073

Context Info Confidence 0.32 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 1 Disease Relevance 0.25 Pain Relevance 0.76

aging (Fos) extracellular region (Pnoc) nucleolus (Fos) nucleus (Fos) DNA binding (Fos) transcription factor binding (Fos)

Anatomy Link Frequency spinal cord 2 Pnoc (Rattus norvegicus) Fos (Rattus norvegicus)

Pain Link Frequency Relevance Heat orphanin 11 100.00 Spinal cord 1 99.68 intrathecal 2 98.56 spinal dorsal horn 1 72.08 opioid receptor 2 69.76 antagonist 3 64.84 narcan 1 61.12 analgesia 1 46.32

Disease Link Frequency Relevance Heat Nociception 4 100.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Spinal nociceptin inhibits AMPA-induced nociceptive behavior and Fos expression in rat spinal cord.

nociceptin Negative_regulation (inhibits) of Gene_expression (expression) of Fos in spinal cord associated with nociception, orphanin and spinal cord

1) Confidence 0.32 Published 2003 Journal Pharmacol. Biochem. Behav. Section Title Doc Link 12543232 Disease Relevance 0.25 Pain Relevance 0.76

General Comments

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