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Context Info
Confidence 0.36
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.62
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CAMK4) nucleoplasm (CAMK4) signal transduction (CAMK4)
nucleus (CAMK4) cytoplasm (CAMK4)
Anatomy Link Frequency
sciatic nerve 1
CAMK4 (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 8 99.32 Very High Very High Very High
Sciatic nerve 15 97.64 Very High Very High Very High
Spinal cord 14 96.24 Very High Very High Very High
alcohol 1 81.68 Quite High
Central nervous system 8 47.40 Quite Low
headache 2 35.52 Quite Low
lumbar region 1 19.60 Low Low
imagery 7 5.00 Very Low Very Low Very Low
positron emission tomography 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 17 99.80 Very High Very High Very High
Depression 8 99.32 Very High Very High Very High
Mental Disorders 1 98.62 Very High Very High Very High
Necrosis 3 89.08 High High
Cancer 75 88.52 High High
Solid Tumor 8 87.32 High High
Ovarian Cancer 100 79.04 Quite High
Injury 3 60.40 Quite High
Apoptosis 29 54.16 Quite High
Metastasis 3 53.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Offspring from crosses of BEG and CaMK-tta transgenic mice were subjected to complete unilateral sciatic nerve axotomy at postnatal day 5 (P5).
CaMK Binding (crosses) of in sciatic nerve associated with targeted disruption and sciatic nerve
1) Confidence 0.36 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2844381 Disease Relevance 0.21 Pain Relevance 0.26
Forty-five adult outpatients who met the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, for major depression based on the structured clinical interview for DSM IV participated in the trial.
DSM IV Binding (interview) of associated with mental disorders and depression
2) Confidence 0.28 Published 2003 Journal Prog. Neuropsychopharmacol. Biol. Psychiatry Section Abstract Doc Link 12551734 Disease Relevance 0.61 Pain Relevance 0.29
Combretastatin A-4 (CA-4), its prodrug ZD6126 and AVE8062 (a water-soluble analog of CA-4) are tubulin-binding agents that are structurally related to the colchicines and possess potent antivascular properties [126].
A-4 Binding (binding) of
3) Confidence 0.01 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2804796 Disease Relevance 0.80 Pain Relevance 0

General Comments

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