INT108243

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Context Info
Confidence 0.34
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.85
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prdx2) mitochondrion (Prdx2) oxidoreductase activity (Prdx2)
cytoplasm (Prdx2)
Anatomy Link Frequency
tears 1
Prdx2 (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 10 96.68 Very High Very High Very High
Inflammation 33 90.12 High High
cytokine 12 5.00 Very Low Very Low Very Low
fibrosis 8 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Burns 10 95.64 Very High Very High Very High
Body Weight 1 90.88 High High
INFLAMMATION 34 90.12 High High
Lung Injury 38 71.36 Quite High
Adult Respiratory Distress Syndrome 20 60.08 Quite High
Keloid Scars 4 57.72 Quite High
Fibrosis 9 5.00 Very Low Very Low Very Low
Injury 7 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In TSA levels, the age-associated increase was greater in males and much lower in females, with higher TSA levels in younger (2.5, 4.5 months) and decreased levels in older female mice (9 months) being observed.
Positive_regulation (increase) of TSA
1) Confidence 0.34 Published 2002 Journal Exp. Gerontol. Section Abstract Doc Link 12559410 Disease Relevance 0.09 Pain Relevance 0.81
The intraperitoneal administration of TSA was chosen over topical administration on the eye to avoid washing TSA from the ocular surface by the tears.
Positive_regulation (washing) of TSA in tears
2) Confidence 0.28 Published 2010 Journal Molecular Vision Section Body Doc Link PMC3013068 Disease Relevance 0.44 Pain Relevance 0.14
Treatment with doxycycline resulted in a decrease of pulmonary MMP-9 activity as well as in an increase in the levels of soluble receptor for advanced glycation endproduct, apoliporotein A-I, peroxiredoxin II, four molecular forms of albumin and two unnamed proteins.
Positive_regulation (increase) of peroxiredoxin II
3) Confidence 0.02 Published 2010 Journal Proteome Sci Section Abstract Doc Link PMC2824689 Disease Relevance 0.32 Pain Relevance 0

General Comments

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