INT108281

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 2000
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 3.10
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ATPase activity (Cftr) enzyme binding (Cftr) molecular_function (Cftr)
protein complex (Cftr) transmembrane transport (Cftr) cytoplasm (Cftr)
Cftr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fibrosis 49 100.00 Very High Very High Very High
Chronic pancreatitis 8 100.00 Very High Very High Very High
Prostatitis 68 97.96 Very High Very High Very High
cytokine 14 88.48 High High
Inflammation 32 88.08 High High
Inflammatory response 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cystic Fibrosis 49 100.00 Very High Very High Very High
Pancreatitis 24 100.00 Very High Very High Very High
Prostatitis 68 97.96 Very High Very High Very High
Bacterial Infection 23 92.20 High High
Disease 17 89.84 High High
Infection 6 88.88 High High
INFLAMMATION 34 88.08 High High
Sinusitis 6 67.20 Quite High
Anxiety Disorder 2 34.00 Quite Low
Malignant Neoplastic Disease 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Current data suggest that the 'chronic complications' reveal mainly the effect of a long-term absence of previously recognized CFTR functions.
Negative_regulation (absence) of CFTR Binding (recognized) of
1) Confidence 0.43 Published 2000 Journal Respir Res Section Abstract Doc Link PMC59552 Disease Relevance 0.60 Pain Relevance 0.26
Interestingly, recent studies have indicated the possible involvement of defective CFTR-mediated HCO3?
Spec (possible) Negative_regulation (possible) of CFTR-mediated Binding (involvement) of
2) Confidence 0.31 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2998414 Disease Relevance 1.20 Pain Relevance 0.51
Mutations of three major genes are associated with an increased risk of acute and chronic pancreatitis: the cationic trypsinogen (PRSS1) gene, the cystic fibrosis transmembrane conductance regulator (CFTR) gene, and the pancreatic secretory trypsin inhibitor (PSTI) or serine protease inhibitor, Kazal type 1 (SPINK1) gene.
Negative_regulation (inhibitor) of CFTR Binding (associated) of associated with fibrosis, cystic fibrosis and chronic pancreatitis
3) Confidence 0.17 Published 2003 Journal Can. J. Gastroenterol. Section Abstract Doc Link 12560855 Disease Relevance 0.65 Pain Relevance 0.31
Mutations of three major genes are associated with an increased risk of acute and chronic pancreatitis: the cationic trypsinogen (PRSS1) gene, the cystic fibrosis transmembrane conductance regulator (CFTR) gene, and the pancreatic secretory trypsin inhibitor (PSTI) or serine protease inhibitor, Kazal type 1 (SPINK1) gene.
Negative_regulation (inhibitor) of cystic fibrosis transmembrane conductance regulator Binding (associated) of associated with fibrosis, cystic fibrosis and chronic pancreatitis
4) Confidence 0.17 Published 2003 Journal Can. J. Gastroenterol. Section Abstract Doc Link 12560855 Disease Relevance 0.65 Pain Relevance 0.31

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox