INT10829

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.34
First Reported 1984
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 12
Total Number 13
Disease Relevance 8.12
Pain Relevance 1.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ldlr) transport (Ldlr) aging (Ldlr)
plasma membrane (Ldlr) lipid metabolic process (Ldlr) lysosome (Ldlr)
Anatomy Link Frequency
blood 1
plasma 1
body 1
Ldlr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
diclofenac 8 100.00 Very High Very High Very High
Pain 6 100.00 Very High Very High Very High
alcohol 5 97.02 Very High Very High Very High
cINOD 2 96.56 Very High Very High Very High
beta blocker 3 95.36 Very High Very High Very High
Inflammation 8 95.08 Very High Very High Very High
anesthesia 2 88.64 High High
Restless leg syndrome 11 79.48 Quite High
Angina 7 77.04 Quite High
abdominal pain 1 50.56 Quite High
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 60 100.00 Very High Very High Very High
Hyperlipidemia 37 99.74 Very High Very High Very High
Peripheral Arterial Disease 12 99.64 Very High Very High Very High
Stress 12 97.42 Very High Very High Very High
Nicotine Addiction 5 96.84 Very High Very High Very High
Obesity 42 96.66 Very High Very High Very High
Diabetes Mellitus 56 96.52 Very High Very High Very High
Aging 2 96.48 Very High Very High Very High
Cancer 2 96.08 Very High Very High Very High
INFLAMMATION 8 95.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The percent changes of total cholesterol, LDL-cholesterol and both ratios were larger in the policosanol group than in the acipimox group.
Regulation (changes) of LDL-cholesterol associated with disorder of lipid metabolism
1) Confidence 0.34 Published 1999 Journal Int J Tissue React Section Abstract Doc Link 10645516 Disease Relevance 0.63 Pain Relevance 0
BACKGROUND: Low-density lipoprotein (LDL) apheresis is effective in the treatment of peripheral arterial occlusive disease (PAOD).
Regulation (effective) of Low-density lipoprotein associated with peripheral arterial disease
2) Confidence 0.21 Published 2007 Journal Am. J. Nephrol. Section Abstract Doc Link 17878713 Disease Relevance 0.27 Pain Relevance 0
The mean percent change in LDL-cholesterol levels from baseline was -24.8% (p < 0.001), and 82.6% of patients achieved an LDL-cholesterol reduction of > or = 15%.
Regulation (change) of LDL-cholesterol
3) Confidence 0.17 Published 1994 Journal Am. J. Med. Section Abstract Doc Link 8017473 Disease Relevance 0.30 Pain Relevance 0.05
Beneficial effects of diclofenac therapy on serum lipids, oxidized low-density lipoprotein and antioxidant defenses in rats.
Regulation (effects) of low-density lipoprotein associated with diclofenac
4) Confidence 0.17 Published 2008 Journal Life Sci. Section Title Doc Link 18342892 Disease Relevance 0.19 Pain Relevance 0.50
Low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) levels were calculated adopting the prescribed formula.

2.7.

Regulation (calculated) of Low-density lipoprotein
5) Confidence 0.14 Published 2010 Journal Journal of Nutrition and Metabolism Section Body Doc Link PMC3018644 Disease Relevance 0.44 Pain Relevance 0.09
Low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) levels were calculated adopting the prescribed formula.

2.7.

Regulation (calculated) of low-density lipoprotein
6) Confidence 0.14 Published 2010 Journal Journal of Nutrition and Metabolism Section Body Doc Link PMC3018644 Disease Relevance 0.44 Pain Relevance 0.09
Efficacy of low-density lipoprotein apheresis in patients with peripheral arterial occlusive disease undergoing hemodialysis treatment.
Regulation (Efficacy) of low-density lipoprotein associated with pain and peripheral arterial disease
7) Confidence 0.11 Published 2007 Journal Am. J. Nephrol. Section Title Doc Link 17878713 Disease Relevance 0.28 Pain Relevance 0.10
The first is collecting the clinical data required by the guidelines for stratifying risk as high (LDL-cholesterol target of ?
Regulation (target) of LDL-cholesterol
8) Confidence 0.07 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988621 Disease Relevance 0.16 Pain Relevance 0
Assignment of these patients to LDL-cholesterol targets of 130 mg/dL was incorrect for failure in data collection but was consistent internally with the data collected by CLEOS®.
Regulation (targets) of LDL-cholesterol
9) Confidence 0.07 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988621 Disease Relevance 0.88 Pain Relevance 0.15
Adjustment for age, body mass index, smoking, alcohol consumption, stress and tension at work, shift work, noise exposure and educational level in multiple linear regression analysis showed significant effects of the CS2 index on systolic BP, diastolic BP, cholesterol, HDL-cholesterol, LDL-cholesterol, apolipoprotein A1, apolipoprotein B, the LDL cholesterol/apolipoprotein B and HDL cholesterol/apolipoprotein A1 ratios; there were no significant effects on the triglycerides.
Regulation (effects) of LDL-cholesterol in body associated with stress, nicotine addiction, obesity, disorder of lipid metabolism and alcohol
10) Confidence 0.06 Published 1992 Journal Int J Epidemiol Section Abstract Doc Link 1521980 Disease Relevance 1.55 Pain Relevance 0.21
The thiazides hydrochlorothiazide and chlorthalidone cause an elevation of plasma triglycerides and very low density lipoprotein (VLDL) but have little effect on total cholesterol, low density lipoprotein (LDL) and high density lipoprotein (HDL).
Neg (little) Regulation (effect) of low density lipoprotein in plasma associated with disorder of lipid metabolism
11) Confidence 0.04 Published 1984 Journal Klin. Wochenschr. Section Abstract Doc Link 6143851 Disease Relevance 0.78 Pain Relevance 0.12
In comparison with baseline values, no significant change was observed in blood glucose, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, creatinine, TBARS and TAP in placebo-treated group.
Neg (no) Regulation (change) of LDL-cholesterol in blood associated with disorder of lipid metabolism
12) Confidence 0.01 Published 2010 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Abstract Doc Link PMC2892343 Disease Relevance 1.03 Pain Relevance 0
Therefore, WJ diet may improve the status of hypercholesterolemia through the modulation of HDL, LDL-cholesterol and anti-oxidant system.
Regulation (modulation) of LDL-cholesterol associated with hyperlipidemia and disorder of lipid metabolism
13) Confidence 0.00 Published 2010 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2892354 Disease Relevance 1.18 Pain Relevance 0.05

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox