INT108330

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Context Info
Confidence 0.41
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.15
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (EGF, EPHB2) signal transduction (EGF) extracellular space (EGF)
extracellular region (EGF)
EGF (Homo sapiens)
EPHB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 78.00 Quite High
Disease Link Frequency Relevance Heat
Cancer 5 96.48 Very High Very High Very High
Colon Cancer 6 86.04 High High
INFLAMMATION 2 77.76 Quite High
Apoptosis 2 75.24 Quite High
Death 2 63.24 Quite High
Rectal Cancer 1 61.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ability of sulindac to block ERK1/2 signaling by the EGF receptor may account for at least part of its potent growth-inhibitory effects against cancer cells.
EGF Negative_regulation (block) of ERK associated with cancer
1) Confidence 0.41 Published 2003 Journal Cancer Res. Section Abstract Doc Link 12566304 Disease Relevance 1.15 Pain Relevance 0.13

General Comments

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