INT108347

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Context Info
Confidence 0.26
First Reported 2003
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 2.55
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Adm) extracellular region (Adm) response to stress (Adm)
cytoplasm (Adm)
Anatomy Link Frequency
plasma 1
cerebral cortex 1
Adm (Mus musculus)
Pain Link Frequency Relevance Heat
spinal inflammation 4 99.56 Very High Very High Very High
cerebral cortex 6 98.68 Very High Very High Very High
headache 3 93.68 High High
Inflammation 3 91.56 High High
Pyramidal cell 3 87.44 High High
anesthesia 2 50.00 Quite Low
Disease Link Frequency Relevance Heat
Low Back Pain 4 99.56 Very High Very High Very High
Familial Mediterranean Fever 4 98.48 Very High Very High Very High
Hypoxia 9 98.44 Very High Very High Very High
Vomiting 3 94.12 High High
Headache 3 93.68 High High
Dizziness 3 92.44 High High
Sleep Disorders 3 92.00 High High
INFLAMMATION 3 91.56 High High
Disease 2 88.64 High High
Fever 1 78.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Circulating adrenomedullin levels in ankylosing spondylitis and Familial Mediterranean Fever.
Regulation (Circulating) of adrenomedullin associated with spinal inflammation and familial mediterranean fever
1) Confidence 0.26 Published 2008 Journal Joint Bone Spine Section Title Doc Link 18394945 Disease Relevance 1.04 Pain Relevance 0.47
Multivariate stepwise analysis identified plasma AM as the critical independent factor affecting urinary AQP2/Cr level.
Regulation (affecting) of AM in plasma
2) Confidence 0.14 Published 2003 Journal Horm. Res. Section Body Doc Link 12566732 Disease Relevance 0 Pain Relevance 0
In addition, hypobaria modulates alternative splicing of the AM gene resulting in a higher production of AM.
Regulation (modulates) of AM
3) Confidence 0.04 Published 2008 Journal Brain Pathol. Section Abstract Doc Link 18371176 Disease Relevance 0.45 Pain Relevance 0.17
Our data show that AM expression regulation constitutes a cortical response to hypobaria, suggesting that AM modulation may provide new therapeutic avenues to prevent and/or treat the symptoms produced by hypobaria.
Regulation (regulation) of AM
4) Confidence 0.04 Published 2008 Journal Brain Pathol. Section Abstract Doc Link 18371176 Disease Relevance 0.43 Pain Relevance 0.17
AM immunoreactivity was transiently elevated in the cerebral cortex after 7 h of exposure to a simulated altitude of 8325 m (27 000 ft).
Regulation (immunoreactivity) of AM in cerebral cortex associated with cerebral cortex
5) Confidence 0.04 Published 2008 Journal Brain Pathol. Section Abstract Doc Link 18371176 Disease Relevance 0.64 Pain Relevance 0.22

General Comments

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