INT108367

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Context Info
Confidence 0.13
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Chrm5) cellular_component (Chrm5) signal transducer activity (Chrm5)
Anatomy Link Frequency
spinal cord 1
internal 1
afferent neurons 1
Chrm5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 16 57.52 Quite High
Enkephalin 5 56.88 Quite High
calcitonin gene related peptide 3 56.20 Quite High
Neurotransmitter 19 50.56 Quite High
Morphine 6 50.00 Quite Low
Spinal cord 5 50.00 Quite Low
medulla 4 50.00 Quite Low
Calcium channel 20 5.00 Very Low Very Low Very Low
excitatory amino acid 16 5.00 Very Low Very Low Very Low
agonist 13 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Vomiting 17 20.00 Low Low
Syndrome 8 18.32 Low Low
Vertigo 23 5.00 Very Low Very Low Very Low
Disease 20 5.00 Very Low Very Low Very Low
Nystagmus 11 5.00 Very Low Very Low Very Low
Dizziness 6 5.00 Very Low Very Low Very Low
Headache 5 5.00 Very Low Very Low Very Low
Vestibular Diseases 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Sleep Disorders 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The levels of m1, m2, m3 and m5 in spinal cord were increased by pretreatment with pirenzepine and the levels of m2, m3 and m4 in spinal cord were increased by pretreatment with scopolamine.
Gene_expression (levels) of m5 in spinal cord
1) Confidence 0.13 Published 2002 Journal Yao Xue Xue Bao Section Body Doc Link 12567774 Disease Relevance 0 Pain Relevance 0
METHODS: The mRNA expression level of m1, m2, m3, m4 and m5 were determined by RT-PCR, the beta-actin mRNA expression was used as internal control.
Gene_expression (expression) of m5 in internal
2) Confidence 0.06 Published 2002 Journal Yao Xue Xue Bao Section Body Doc Link 12567774 Disease Relevance 0 Pain Relevance 0
In addition to nicotinic receptors, muscarinic receptors (m1, m2 and m5) were expressed in human vestibular afferent neurons, whereas in the rat, five subtypes of muscarinic receptors (m1 - m5) are found [160].
Gene_expression (expressed) of m5 in afferent neurons
3) Confidence 0.01 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2866460 Disease Relevance 0 Pain Relevance 0.14

General Comments

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