INT108404

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Context Info
Confidence 0.33
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (FAAH) cytoplasm (FAAH)
FAAH (Homo sapiens)
Pain Link Frequency Relevance Heat
Cannabinoid 3 97.76 Very High Very High Very High
Cannabinoid receptor 2 89.76 High High
agonist 2 88.96 High High
qutenza 4 80.32 Quite High
Inflammation 1 77.84 Quite High
Disease Link Frequency Relevance Heat
Breast Cancer 1 99.52 Very High Very High Very High
INFLAMMATION 1 77.84 Quite High
Cancer 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, long-term treatment of human breast cancer cells (HBCCs) with PEA downregulates the expression of the enzyme responsible for AEA degradation, the fatty acid amide hydrolase, thereby leading to an enhancement of AEA-induced, and cannabinoid CB1 receptor-mediated, cytostatic effect on HBCCs.
Negative_regulation (downregulates) of Protein_catabolism (degradation) of fatty acid amide hydrolase associated with cannabinoid and breast cancer
1) Confidence 0.33 Published 2002 Journal Fundam Clin Pharmacol Section Abstract Doc Link 12570018 Disease Relevance 0.25 Pain Relevance 0.41

General Comments

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