INT108438

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Context Info
Confidence 0.16
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grin2b, Pdyn) transport (Grin2b) embryo development (Grin2b)
Grin2b (Mus musculus)
Pdyn (Mus musculus)
Pain Link Frequency Relevance Heat
Dynorphin 15 100.00 Very High Very High Very High
nMDA receptor 5 100.00 Very High Very High Very High
antagonist 3 100.00 Very High Very High Very High
Opioid 3 99.90 Very High Very High Very High
Antinociceptive 1 95.40 Very High Very High Very High
Endogenous opioid 1 94.12 High High
Spinal cord 2 91.04 High High
Glutamate 2 25.00 Low Low
narcan 1 25.00 Low Low
opioid receptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Toxicity 6 99.96 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both kappa-opioid and N-methyl-D-aspartate receptor antagonists modulate dynorphin toxicity, suggesting that dynorphin is acting directly or indirectly through these receptor types.
N-methyl-D-aspartate receptor Regulation (modulate) of dynorphin associated with toxicity, dynorphin, antagonist, nmda receptor and opioid
1) Confidence 0.16 Published 2003 Journal Neuroscience Section Abstract Doc Link 12573721 Disease Relevance 0.25 Pain Relevance 0.90

General Comments

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