INT108471

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Context Info
Confidence 0.29
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.64
Pain Relevance 3.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CALCA, PNOC) aging (CALCA) intracellular (CALCA)
cell-cell signaling (CALCA) cytoplasm (CALCA) extracellular space (CALCA)
Anatomy Link Frequency
pituitary 2
CALCA (Homo sapiens)
PNOC (Homo sapiens)
Pain Link Frequency Relevance Heat
orphanin 60 100.00 Very High Very High Very High
Calcitonin gene-related peptide 15 100.00 Very High Very High Very High
trigeminal ganglion 9 99.98 Very High Very High Very High
substance P 12 99.92 Very High Very High Very High
Opioid 6 72.20 Quite High
Neuropeptide 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 9 99.98 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Double immunostaining showed that in the human trigeminal ganglion nociceptin colocalized with calcitonin gene-related peptide (CGRP), substance P (SP), nitric oxide synthase (NOS) or pituitary adenylate cyclase activating peptide (PACAP).
calcitonin gene-related peptide Binding (colocalized) of nociceptin in pituitary associated with ganglion cysts, orphanin, trigeminal ganglion, substance p and calcitonin gene-related peptide
1) Confidence 0.29 Published 2003 Journal Brain Res. Section Abstract Doc Link 12576178 Disease Relevance 0.25 Pain Relevance 1.14
Double immunostaining showed that in the human trigeminal ganglion nociceptin colocalized with calcitonin gene-related peptide (CGRP), substance P (SP), nitric oxide synthase (NOS) or pituitary adenylate cyclase activating peptide (PACAP).
CGRP Binding (colocalized) of nociceptin in pituitary associated with ganglion cysts, orphanin, trigeminal ganglion, substance p and calcitonin gene-related peptide
2) Confidence 0.29 Published 2003 Journal Brain Res. Section Abstract Doc Link 12576178 Disease Relevance 0.25 Pain Relevance 1.14
Nociceptin is colocalized with CGRP, SP, NOS and PACAP.
CGRP Binding (colocalized) of Nociceptin associated with orphanin, substance p and calcitonin gene-related peptide
3) Confidence 0.28 Published 2003 Journal Brain Res. Section Abstract Doc Link 12576178 Disease Relevance 0.14 Pain Relevance 0.96

General Comments

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