INT108501

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Context Info
Confidence 0.32
First Reported 2003
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 14
Total Number 17
Disease Relevance 11.50
Pain Relevance 2.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lysosome (ARSD)
Anatomy Link Frequency
neuron 1
bowel 1
heart 1
ARSD (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 17 99.76 Very High Very High Very High
Anterior cingulate cortex 189 99.30 Very High Very High Very High
rheumatoid arthritis 76 98.44 Very High Very High Very High
Fibrositis 194 98.20 Very High Very High Very High
Pain 63 94.60 High High
spastic colon 8 91.60 High High
headache 2 90.24 High High
Leflunomide 5 83.40 Quite High
Transcranial magnetic stimulation 10 82.88 Quite High
cINOD 6 82.88 Quite High
Disease Link Frequency Relevance Heat
Cognitive Disorder 89 100.00 Very High Very High Very High
Anxiety Disorder 54 100.00 Very High Very High Very High
Disease 20 100.00 Very High Very High Very High
Cv General 2 Under Development 8 100.00 Very High Very High Very High
Headache 18 99.76 Very High Very High Very High
Depression 22 99.60 Very High Very High Very High
Low Back Pain 3 98.96 Very High Very High Very High
Autism 200 98.60 Very High Very High Very High
Rheumatoid Arthritis 76 98.44 Very High Very High Very High
Fibromyalgia 188 98.20 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While previous work has focused largely on interpersonal cognition in autism, a recent shift has been towards understanding altered intrapersonal cognition in ASD.
ASD Binding (cognition) of associated with cognitive disorder and autism
1) Confidence 0.32 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2568959 Disease Relevance 0.82 Pain Relevance 0.04
The mechanisms implemented by the rIFG likely mediate differences between ASD and TD children in social interactions that are more complex than those tapped by our self-other discrimination task.
ASD Binding (interactions) of
2) Confidence 0.32 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2568959 Disease Relevance 0.15 Pain Relevance 0.06
Subsequent investigations found no associations between MV exposure and ASD but did not test for the presence of MV RNA in bowel or focus on children with ASD and GI disturbances.
ASD Neg (no) Binding (associations) of in bowel
3) Confidence 0.31 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2526159 Disease Relevance 0.97 Pain Relevance 0.03
While previous work has largely emphasized deficits in interpersonal interaction in ASD, current empirical work emphasizes the need for understanding differences with respect to both interpersonal (social) and intrapersonal (self-referential) cognition [10].
ASD Binding (interaction) of associated with cognitive disorder
4) Confidence 0.30 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2568959 Disease Relevance 0.19 Pain Relevance 0
This result is consistent with behavioral work demonstrating successful visual self-recognition in most children with ASD [28], [29], [49].
ASD Binding (recognition) of
5) Confidence 0.30 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2568959 Disease Relevance 0.06 Pain Relevance 0
Similar to individuals with OCD, ASD participants showed an exaggerated ACC response to correct trials (Ursu et al., 2003; Maltby et al., 2005).
ASD Binding (individuals) of associated with anxiety disorder and anterior cingulate cortex
6) Confidence 0.29 Published 2008 Journal Brain Section Body Doc Link PMC2525446 Disease Relevance 0.51 Pain Relevance 0.10
More generally, the relations we observed between behavioural repetition and ACC function and structure may not be specific to ASD.
ASD Binding (specific) of associated with anterior cingulate cortex
7) Confidence 0.29 Published 2008 Journal Brain Section Body Doc Link PMC2525446 Disease Relevance 0.30 Pain Relevance 0.12
To determine the magnitude of the association between atrial septal defect (ASD) and migraine.
ASD Binding (association) of associated with cv general 2 under development and migraine
8) Confidence 0.27 Published 2005 Journal Arq Neuropsiquiatr Section Abstract Doc Link 16400426 Disease Relevance 1.07 Pain Relevance 0.57
Two predictions of the ASD hypothesis were tested: that ASD, taken as a single entity, would aggregate in families and that MDD would coaggregate with other forms of ASD in families.
ASD Binding (aggregate) of associated with depression
9) Confidence 0.25 Published 2003 Journal Arch. Gen. Psychiatry Section Abstract Doc Link 12578434 Disease Relevance 1.54 Pain Relevance 0.27
CONCLUSIONS: Affective spectrum disorder aggregates strongly in families, and MDD displays a significant familial coaggregation with other forms of ASD, taken collectively.
ASD Binding (coaggregation) of
10) Confidence 0.25 Published 2003 Journal Arch. Gen. Psychiatry Section Body Doc Link 12578434 Disease Relevance 0 Pain Relevance 0
Here we report independent, blinded analysis of ileal and cecal tissues from children with ASD and GI disturbances and children with GI disturbances but no neurological deficits for the presence of MV RNA in three laboratories, including the one where the original reports of an association between ASD and MV were obtained.


ASD Binding (association) of
11) Confidence 0.23 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2526159 Disease Relevance 0.59 Pain Relevance 0
Thus, ASD was found to strongly aggregate in families and major depressive disorder displayed a significant familial co-aggregation with other forms of ASD, suggesting a shared genetic and pathophysiological basis for these disorders [29].
ASD Binding (aggregate) of associated with depression
12) Confidence 0.23 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779444 Disease Relevance 1.64 Pain Relevance 0.33
Indeed, Hudson and colleagues [28] reported on familial aggregation of ASD collectively and familial co-aggregation of FMS with other forms of ASD.
ASD Binding (aggregation) of associated with fibrositis
13) Confidence 0.20 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779444 Disease Relevance 1.75 Pain Relevance 0.62
From this information and from our present study, it is very likely that therapy with ASD and testosterone can be beneficial in RA patients.
ASD Binding (therapy) of associated with rheumatoid arthritis
14) Confidence 0.18 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1257423 Disease Relevance 1.10 Pain Relevance 0.61
Burgeoning research efforts suggest that a deficient mirror neuron system may contribute to motor and social problems experienced in individuals with ASD.
ASD Binding (individuals) of in neuron
15) Confidence 0.18 Published 2007 Journal Biopsychosoc Med Section Body Doc Link PMC2206036 Disease Relevance 0.27 Pain Relevance 0.11
Patients with an interatrial shunt were identified, and those with any other form of congenital heart disease or an inheritable syndrome associated with ASD were excluded.
ASD Binding (associated) of in heart
16) Confidence 0.15 Published 2009 Journal Congenit Heart Dis Section Body Doc Link 19925540 Disease Relevance 0.26 Pain Relevance 0
The aim of this retrospective study was to evaluate a group of patients with adjacent segment disease (ASD) developed after 360-degrees lumbar fusion for spondylolisthesis performed by PLIF with transpedicular fixation and posterolateral fusion (PLF).Radiographic examinations were focused on the origin or progression of degenerative changes at the adjacent segments after the operation, with statistical evaluation of some parameters.
ASD Binding (group) of associated with low back pain and disease
17) Confidence 0.05 Published 2010 Journal Acta Chir Orthop Traumatol Cech Section Abstract Doc Link 20447355 Disease Relevance 0.27 Pain Relevance 0.07

General Comments

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