INT10851

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Context Info
Confidence 0.57
First Reported 1992
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.54
Pain Relevance 2.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (LAMC2) extracellular region (LAMC2) cell adhesion (LAMC2)
Anatomy Link Frequency
CSF 4
LAMC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 7 99.48 Very High Very High Very High
Migraine 14 98.64 Very High Very High Very High
headache 7 98.12 Very High Very High Very High
central sensitization 1 96.44 Very High Very High Very High
Fibrositis 8 96.36 Very High Very High Very High
Neuropeptide 1 87.04 High High
Analgesic 4 85.92 High High
Lasting pain 1 76.00 Quite High
backache 1 66.20 Quite High
Disease Link Frequency Relevance Heat
Disease 4 99.62 Very High Very High Very High
Headache 20 98.64 Very High Very High Very High
Dementia 1 97.44 Very High Very High Very High
Fibromyalgia 6 96.36 Very High Very High Very High
Low Back Pain 1 66.20 Quite High
Migraine Without Aura 1 63.96 Quite High
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Data from the one patient with Pick's disease demonstrates that reduced CSF levels of neurophysins and hormones is not confined to Alzheimer-type dementia.
Negative_regulation (reduced) of Gene_expression (levels) of CSF in CSF associated with dementia and disease
1) Confidence 0.57 Published 1992 Journal Neurobiol. Aging Section Abstract Doc Link 1522943 Disease Relevance 0.45 Pain Relevance 0.11
Based on experimental findings, it can be postulated that reduced CSF levels of GDNF and somatostatin in both CM and PCM + PAAH patients can contribute to sustained central sensitization underlying chronic head pain.
Negative_regulation (reduced) of Gene_expression (levels) of CSF in CSF associated with central sensitization, migraine, somatostatin and headache
2) Confidence 0.41 Published 2006 Journal Cephalalgia Section Abstract Doc Link 16556241 Disease Relevance 2.09 Pain Relevance 2.57

General Comments

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