INT108587

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.57
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.73
Pain Relevance 1.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PSMA5) nucleoplasm (PSMA5) peptidase activity (PSMA5)
small molecule metabolic process (PSMA5) nucleolus (PSMA5) nucleus (PSMA5)
PSMA5 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 16 99.84 Very High Very High Very High
Kinase C 6 92.56 High High
Disease Link Frequency Relevance Heat
Apoptosis 20 98.00 Very High Very High Very High
INFLAMMATION 4 83.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among the signaling molecules modulated by NO, NSAIDs blocked NO-induced activation of p38 kinase, potentiated ERK activation, and blocked inhibition of PKCalpha and -zeta.
Negative_regulation (inhibition) of zeta associated with cinod
1) Confidence 0.57 Published 2003 Journal J. Biol. Chem. Section Abstract Doc Link 12588866 Disease Relevance 0.92 Pain Relevance 0.75
NO production also caused inhibition of PKCalpha and -zeta independent of and dependent on, respectively, p38 kinase, which is required for apoptosis and dedifferentiation.
Negative_regulation (inhibition) of zeta associated with apoptosis
2) Confidence 0.57 Published 2003 Journal J. Biol. Chem. Section Abstract Doc Link 12588866 Disease Relevance 0.82 Pain Relevance 0.67

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox