INT108602

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Context Info
Confidence 0.22
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (NTRK2) plasma membrane (NTRK2)
NTRK2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dorsal horn 1 97.68 Very High Very High Very High
Neuropathic pain 1 92.32 High High
Inflammation 2 91.48 High High
c fibre 1 88.16 High High
spinal dorsal horn 1 85.64 High High
Peripheral nervous system 1 77.88 Quite High
Hyperalgesia 1 76.80 Quite High
Nerve growth factor 1 73.84 Quite High
Thermal hyperalgesia 1 70.24 Quite High
Neurotransmitter 1 51.44 Quite High
Disease Link Frequency Relevance Heat
Nociception 3 99.66 Very High Very High Very High
Neuropathic Pain 1 92.32 High High
INFLAMMATION 2 91.48 High High
Hyperalgesia 2 76.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Stimulation of pre-synaptic nociceptive afferent fibres induces BDNF release and consequent activation of TrkB receptors leading to a post-synaptic excitability.
Positive_regulation (induces) of Positive_regulation (activation) of TrkB associated with nociception
1) Confidence 0.22 Published 2002 Journal Brain Res. Brain Res. Rev. Section Abstract Doc Link 12589922 Disease Relevance 0.56 Pain Relevance 0.60

General Comments

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