INT10861

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Context Info
Confidence 0.11
First Reported 1992
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 3.22
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Vldlr) extracellular space (Vldlr) nucleus (Vldlr)
Anatomy Link Frequency
blood 1
Vldlr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 2 76.24 Quite High
tolerance 4 74.40 Quite High
abdominal pain 1 64.96 Quite High
depression 1 60.88 Quite High
Pain 1 28.64 Quite Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 4 99.92 Very High Very High Very High
Hyperlipidemia 14 99.90 Very High Very High Very High
Disorder Of Lipid Metabolism 22 97.64 Very High Very High Very High
Obesity 11 93.76 High High
Renal Failure 2 92.84 High High
Chronic Renal Failure 2 90.72 High High
Diabetes Mellitus 62 84.16 Quite High
Necrosis 1 77.16 Quite High
Abdominal Pain 1 64.96 Quite High
Exanthema 1 63.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Very-low-density lipoprotein (VLDL) levels were reduced by approximately 50% after treatment, accompanied by a marked increase of lipoprotein lipase (LPL) and hepatic triglyceride lipase (HTGL) activity.
Negative_regulation (reduced) of Very-low-density lipoprotein
1) Confidence 0.11 Published 1993 Journal Metab. Clin. Exp. Section Abstract Doc Link 8345799 Disease Relevance 0.68 Pain Relevance 0.09
In all types of HLP the reduction of serum cholesterol (CH), triglycerides (TG), very low density lipoprotein (VLDL) fraction and increase in high density lipoprotein (HDL) cholesterol, HDL3-CH and apolipoprotein AI concentrations was observed.
Negative_regulation (reduction) of very low density lipoprotein associated with hyperlipidemia and disorder of lipid metabolism
2) Confidence 0.10 Published 1992 Journal Pol. Arch. Med. Wewn. Section Abstract Doc Link 1523145 Disease Relevance 0.93 Pain Relevance 0.06
LDL-cholesterol, Lp(a), and very-low-density lipoprotein (VLDL)-cholesterol were effectively reduced while the decrease of triglycerides and fibrinogen was only moderate.
Negative_regulation (reduced) of very-low-density lipoprotein
3) Confidence 0.09 Published 2001 Journal Ther Apher Section Abstract Doc Link 11778922 Disease Relevance 0.07 Pain Relevance 0.11
Serum and very-low density lipoprotein (VLDL) triglyceride were decreased by 36% and 48%, respectively.
Negative_regulation (decreased) of very-low density lipoprotein
4) Confidence 0.07 Published 1993 Journal Kidney Int. Section Abstract Doc Link 8301936 Disease Relevance 0.75 Pain Relevance 0
Following 30 days treatment with MCE at 150 & 300 mg/kg doses, the rats showed dose dependent reduction in cholesterol, triglyceride, LDL-CH, VLDL-CH and blood glucose levels as compared to untreated control.
Negative_regulation (reduction) of VLDL-CH in blood
5) Confidence 0.05 Published 2007 Journal BMC Complement Altern Med Section Body Doc Link PMC2048984 Disease Relevance 0.79 Pain Relevance 0

General Comments

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