INT10862

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Context Info
Confidence 0.15
First Reported 1987
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 2.96
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Vldlr) extracellular space (Vldlr) nucleus (Vldlr)
Anatomy Link Frequency
plasma 1
Vldlr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
abdominal pain 2 96.84 Very High Very High Very High
Angina 3 91.88 High High
Central nervous system 1 80.56 Quite High
antagonist 3 63.76 Quite High
corticosteroid 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 7 98.80 Very High Very High Very High
Hyperlipidemia 7 98.76 Very High Very High Very High
Hypertension 6 98.12 Very High Very High Very High
Abdominal Pain 2 96.84 Very High Very High Very High
Cardiovascular Disease 1 95.36 Very High Very High Very High
Pancreatitis 3 93.68 High High
Myocardial Infarction 2 91.96 High High
Stable Angina Pectoris 3 91.88 High High
Recurrence 2 88.48 High High
Leukemia 7 84.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increases in plasma levels of both total triglycerides and very low density lipoprotein (VLDL) triglycerides have accompanied atenolol therapy although the clinical relevance, if any, of longer term metabolic effects has yet to be determined.
Positive_regulation (Increases) of very low density lipoprotein in plasma
1) Confidence 0.15 Published 1991 Journal Drugs Section Abstract Doc Link 1720383 Disease Relevance 0.88 Pain Relevance 0.24
Nuclear magnetic resonance analysis of lipid subclasses showed a significant increase in the smaller, denser forms of very low density lipoprotein (VLDL) and negligible chylomicron fraction in a subset of patients with marked triglyceride elevation.
Positive_regulation (increase) of very low density lipoprotein
2) Confidence 0.08 Published 1997 Journal Blood Section Abstract Doc Link 9058708 Disease Relevance 0.95 Pain Relevance 0.10
In all types of HLP the reduction of serum cholesterol (CH), triglycerides (TG), very low density lipoprotein (VLDL) fraction and increase in high density lipoprotein (HDL) cholesterol, HDL3-CH and apolipoprotein AI concentrations was observed.
Positive_regulation (increase) of very low density lipoprotein associated with hyperlipidemia and disorder of lipid metabolism
3) Confidence 0.08 Published 1992 Journal Pol. Arch. Med. Wewn. Section Abstract Doc Link 1523145 Disease Relevance 0.94 Pain Relevance 0.07
In those taking propranolol, very low density lipoprotein (VLDL) increased at 52 weeks (P less than 0.05) and total high density lipoprotein (HDL) decreased at 26 weeks (P less than 0.01) and at 52 weeks (P less than 0.05).
Positive_regulation (increased) of very low density lipoprotein associated with disorder of lipid metabolism
4) Confidence 0.08 Published 1987 Journal Clin. Sci. Section Abstract Doc Link 3581681 Disease Relevance 0.19 Pain Relevance 0.09

General Comments

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