INT108622

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Context Info
Confidence 0.47
First Reported 2003
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.18
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Scn10a) transmembrane transport (Scn10a)
Anatomy Link Frequency
skeletal muscle 1
dorsal root ganglion 1
Scn10a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
sodium channel 7 99.92 Very High Very High Very High
dorsal root ganglion 1 98.60 Very High Very High Very High
local anesthetic 3 91.76 High High
Action potential 2 82.92 Quite High
Pain 3 82.88 Quite High
nociceptor 2 81.40 Quite High
tetrodotoxin 1 77.76 Quite High
Neuropeptide 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 98.60 Very High Very High Very High
Pain 1 82.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we report the use of a yeast two-hybrid system and a rat dorsal root ganglion cDNA library to identify 28 different clones encoding proteins which interact with intracellular domains of Na(V)1.8.
Na(V)1.8 Binding (interact) of in dorsal root ganglion associated with ganglion cysts and dorsal root ganglion
1) Confidence 0.47 Published 2003 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12591166 Disease Relevance 0.18 Pain Relevance 0.45
We used computational methods to construct a simple model of benzocaine analog binding with the D4S6 segment of rat skeletal muscle (NaV4.1) sodium channels.
NaV4.1 Binding (binding) of in skeletal muscle associated with sodium channel
2) Confidence 0.30 Published 2005 Journal Biophys. Chem. Section Abstract Doc Link 15617805 Disease Relevance 0 Pain Relevance 0.45

General Comments

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