INT108647

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.33
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.78
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grin2a) nucleus (Camk1d) plasma membrane (Grin2a)
locomotion (Grin2a) kinase activity (Camk1d) cytoplasm (Camk1d)
Anatomy Link Frequency
spinal cord 1
Grin2a (Mus musculus)
Camk1d (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 6 100.00 Very High Very High Very High
Spinal cord 3 99.12 Very High Very High Very High
Inflammation 1 87.84 High High
Neuropathic pain 2 86.84 High High
allodynia 1 85.16 High High
Hyperalgesia 1 84.60 Quite High
Dorsal horn 1 75.24 Quite High
Analgesic 1 65.24 Quite High
Lasting pain 1 63.04 Quite High
Disease Link Frequency Relevance Heat
Nociception 1 88.32 High High
INFLAMMATION 1 87.84 High High
Neuropathic Pain 6 86.84 High High
Hyperalgesia 1 84.60 Quite High
Nervous System Injury 1 63.84 Quite High
Pain 1 63.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In wild-type mice following CCI, CaM kinase II inhibitors attenuate sensitization of behavioral reflexes, elevated constitutive (autophosphorylated) activity of CaM kinase II is detected in spinal cord, and increased amounts of phospho-Thr(286) CaM kinase II coimmunoprecipitate with NMDA receptor NR2A/B subunits.
NR2A Binding (coimmunoprecipitate) of CaM kinase in spinal cord associated with nmda receptor and spinal cord
1) Confidence 0.33 Published 2003 Journal Curr. Biol. Section Abstract Doc Link 12593798 Disease Relevance 0.78 Pain Relevance 0.90

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox