INT108694

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Context Info
Confidence 0.46
First Reported 2003
Last Reported 2003
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (NTF3) extracellular region (NTF3) cytoplasmic membrane-bounded vesicle (NTF3)
plasma membrane (NTF3) cell-cell signaling (NTF3)
Anatomy Link Frequency
ganglia 2
NTF3 (Homo sapiens)
Pain Link Frequency Relevance Heat
trk C 1 100.00 Very High Very High Very High
abdominal pain 1 95.76 Very High Very High Very High
Inflammation 1 93.60 High High
Crohn's disease 1 89.16 High High
potassium channel 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Diarrhoea 1 97.52 Very High Very High Very High
Abdominal Pain 1 95.76 Very High Very High Very High
Inflammatory Bowel Disease 2 90.08 High High
Disease 1 89.16 High High
Neuromuscular Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neurotrophin-3 (NT-3), which regulates IK1 expression, was also observed in fewer neurons of the myenteric ganglia in Crohn's bowel (p = 0.048), and in inflamed colonic extracts by Western blotting (p = 0.004); the numbers of neurons expressing the NT-3 high affinity receptor trk C were unchanged.
Neg (unchanged) Positive_regulation (unchanged) of Gene_expression (expressing) of NT-3 in ganglia associated with trk c
1) Confidence 0.46 Published 2003 Journal Neuroreport Section Abstract Doc Link 12598727 Disease Relevance 0.37 Pain Relevance 0.27

General Comments

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