INT108715

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Context Info
Confidence 0.47
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.95
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Sod3) response to stress (Sod3) cytoplasm (Sod3)
cytosol (Sod3) extracellular space (Sod3) extracellular region (Sod3)
Anatomy Link Frequency
plasma 1
Sod3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 2 99.90 Very High Very High Very High
chemokine 2 75.92 Quite High
cytokine 6 33.36 Quite Low
Inflammation 10 32.96 Quite Low
antagonist 24 5.00 Very Low Very Low Very Low
Serotonin 10 5.00 Very Low Very Low Very Low
fluoxetine 6 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
sSRI 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 5 98.24 Very High Very High Very High
Hypoxia 15 97.28 Very High Very High Very High
Increased Venous Pressure Under Development 9 96.80 Very High Very High Very High
Stress 4 95.80 Very High Very High Very High
Pulmonary Hypertension 300 89.12 High High
Hypertrophy 72 78.52 Quite High
Natriuresis 5 51.76 Quite High
Adhesions 4 39.44 Quite Low
Injury 2 37.20 Quite Low
INFLAMMATION 16 32.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After intratracheal gene transfer, EC-SOD was successfully expressed in lung tissue, bronchoalveolar lavage fluid, and plasma.
Gene_expression (expressed) of EC-SOD in plasma
1) Confidence 0.47 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2843902 Disease Relevance 0.53 Pain Relevance 0.03
Gene transfer of extracellular superoxide dismutase reduces arterial pressure in spontaneously hypertensive rats: role of heparin-binding domain.
Gene_expression (transfer) of extracellular superoxide dismutase associated with anesthesia and hypertension
2) Confidence 0.46 Published 2003 Journal Circ. Res. Section Title Doc Link 12600899 Disease Relevance 0.43 Pain Relevance 0.10
Twenty-eight days after MCT injection, RV systolic pressure and the weight ratio of the RV to the LV plus septum were significantly lower in the AdEC-SOD group than in the MCT group and the Ad?
Gene_expression (group) of AdEC-SOD
3) Confidence 0.45 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2843902 Disease Relevance 0.63 Pain Relevance 0.04
The effects of prolonged ANG II to cause hypertension, renal vasoconstriction, renal cortical hypoxia, and reduced efficiency of O(2) usage for Na(+) transport, activation of NADPH oxidase, increased expression of p22(phox), and reduced expression of EC-SOD can be ascribed to O(2)(-). generation because they are prevented by an SOD mimetic.
Gene_expression (expression) of EC-SOD associated with hypoxia, hypertension and increased venous pressure under development
4) Confidence 0.33 Published 2005 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 15598867 Disease Relevance 0.37 Pain Relevance 0.06

General Comments

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