INT108727

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Context Info
Confidence 0.34
First Reported 2003
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.97
Pain Relevance 1.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (ATP1A2, CACNA1A) cytoplasm (ATP1A2, CACNA1A) plasma membrane (ATP1A2, CACNA1A)
endosome (ATP1A2) small molecule metabolic process (CACNA1A) cell death (CACNA1A)
ATP1A2 (Homo sapiens)
CACNA1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 81 100.00 Very High Very High Very High
headache 3 98.92 Very High Very High Very High
Calcium channel 6 93.68 High High
potassium channel 2 59.04 Quite High
Multiple sclerosis 1 12.72 Low Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Neuronal excitability 1 5.00 Very Low Very Low Very Low
Action potential 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Migraine With Aura 53 100.00 Very High Very High Very High
Headache 2 98.92 Very High Very High Very High
Paresis 1 98.08 Very High Very High Very High
Migraine Disorders 46 83.76 Quite High
Disease 1 82.40 Quite High
Migraine Without Aura 12 78.24 Quite High
Demyelinating Disease 5 53.04 Quite High
Apoptosis 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Convulsion 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further investigation of these FHM susceptibility regions has subsequently implicated a specific ATPase gene ATP1A2 on chromosome 1q23.
ATP1A2 Binding (implicated) of FHM associated with migraine
1) Confidence 0.34 Published 2007 Journal BMC Med Genet Section Body Doc Link PMC2034370 Disease Relevance 1.34 Pain Relevance 0.76
Two chromosomal loci are associated to FHM: FHM1 on chromosome 19 and FHM2 on chromosome 1q21-23.
FHM2 Binding (associated) of FHM associated with migraine
2) Confidence 0.19 Published 2003 Journal Ann. Neurol. Section Abstract Doc Link 12601705 Disease Relevance 0.63 Pain Relevance 0.61

General Comments

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