INT108763

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Context Info
Confidence 0.59
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.12
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
brain 2
Cd81 (Mus musculus)
Pain Link Frequency Relevance Heat
Opioid 2 100.00 Very High Very High Very High
Central nervous system 18 99.12 Very High Very High Very High
glial activation 2 90.08 High High
opioid receptor 1 50.00 Quite Low
Spinal cord 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
peripheral neuropathy 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 65 98.56 Very High Very High Very High
Adhesions 11 92.72 High High
Glioma 48 81.28 Quite High
Ganglion Cysts 5 81.08 Quite High
Apoptosis 11 69.48 Quite High
Body Weight 1 54.32 Quite High
Injury 48 47.36 Quite Low
Sprains And Strains 41 43.36 Quite Low
Gliosis 2 6.28 Low Low
Wound Healing 25 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Blood-brain barrier transport via adsorptive-mediated endocytosis plays a key role in the expression of the potent opioid activity of TAPA in the CNS.
Gene_expression (expression) of TAPA in brain associated with opioid
1) Confidence 0.59 Published 2003 Journal J. Neurochem. Section Abstract Doc Link 12603838 Disease Relevance 0.05 Pain Relevance 0.17
Cd81 expression patterns also strongly correlated with those of Id2 and Lpin1 (r = 0.9215 and r = 0.9483).
Gene_expression (expression) of Cd81
2) Confidence 0.51 Published 2007 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2759132 Disease Relevance 0.21 Pain Relevance 0.09
FAK was highly expressed in the control tumor brains as compared to hUCBSC-treated brain sections, which showed high expression of CD81 (Figure 5B).
Gene_expression (expression) of CD81 in brain associated with cancer
3) Confidence 0.46 Published 2010 Journal Aging (Albany NY) Section Body Doc Link PMC3006022 Disease Relevance 0.86 Pain Relevance 0

General Comments

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