INT108874

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Context Info
Confidence 0.44
First Reported 2001
Last Reported 2008
Negated 2
Speculated 1
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.09
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RELA) nucleoplasm (RELA) aging (RELA)
nucleus (RELA) DNA binding (RELA) transcription factor binding (RELA)
Anatomy Link Frequency
nucleus 1
RELA (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 10 99.70 Very High Very High Very High
COX2 2 99.70 Very High Very High Very High
cINOD 2 94.44 High High
Inflammation 38 86.84 High High
COX-2 inhibitor 4 81.76 Quite High
dexamethasone 2 18.72 Low Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Angina 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stomach Cancer 6 97.48 Very High Very High Very High
INFLAMMATION 45 94.24 High High
Injury 8 61.76 Quite High
Adhesions 14 60.56 Quite High
Atherosclerosis 14 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 10 5.00 Very Low Very Low Very Low
Necrosis 7 5.00 Very Low Very Low Very Low
Cancer 7 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
Cardiovascular Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Suppression of RelA/p65 nuclear translocation independent of IkappaB-alpha degradation by cyclooxygenase-2 inhibitor in gastric cancer.
Neg (independent) Regulation (independent) of Localization (translocation) of RelA associated with aspirin and stomach cancer
1) Confidence 0.44 Published 2003 Journal Oncogene Section Title Doc Link 12606945 Disease Relevance 0.42 Pain Relevance 0.31
Suppression of RelA/p65 nuclear translocation independent of IkappaB-alpha degradation by cyclooxygenase-2 inhibitor in gastric cancer.
Neg (independent) Regulation (independent) of Localization (translocation) of p65 associated with aspirin and stomach cancer
2) Confidence 0.44 Published 2003 Journal Oncogene Section Title Doc Link 12606945 Disease Relevance 0.42 Pain Relevance 0.31
Therefore it can be speculated that a simultaneous administration of antisense RelA p65 and NF-?
Regulation (antisense) of Localization (administration) of p65
3) Confidence 0.41 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0.12 Pain Relevance 0
Therefore it can be speculated that a simultaneous administration of antisense RelA p65 and NF-?
Regulation (antisense) of Localization (administration) of RelA
4) Confidence 0.41 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0.12 Pain Relevance 0
To study the result of the treatment of JNK inhibitor on the translocation of p50 and p65 into the nucleus, we determined the appearance of the p50 and p65 in the nucleus extracts by Western blott.
Spec (determined) Regulation (study) of Localization (translocation) of p65 in nucleus
5) Confidence 0.15 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2442592 Disease Relevance 0 Pain Relevance 0

General Comments

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