INT10890

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Context Info
Confidence 0.36
First Reported 1982
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 11
Total Number 11
Disease Relevance 7.27
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F8) oxidoreductase activity (F8) extracellular region (F8)
cell adhesion (F8)
Anatomy Link Frequency
leukocyte 1
skin 1
platelets 1
F8 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 6 97.28 Very High Very High Very High
Angina 7 97.12 Very High Very High Very High
corticosteroid 1 96.40 Very High Very High Very High
Pain 5 90.68 High High
imagery 1 81.96 Quite High
halothane 60 51.96 Quite High
alcohol 21 50.00 Quite Low
abdominal pain 2 50.00 Quite Low
Inflammation 10 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anaemia 1 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 16 99.84 Very High Very High Very High
Pathologic Constriction 3 99.72 Very High Very High Very High
Hemorrhage 13 99.40 Very High Very High Very High
Renal Failure 1 98.64 Very High Very High Very High
Myocardial Infarction 8 98.62 Very High Very High Very High
Hemorrhagic Diathesis 1 98.60 Very High Very High Very High
Diabetes Mellitus 6 97.80 Very High Very High Very High
Cv General 3 Under Development 6 97.28 Very High Very High Very High
Disease 9 96.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cells collected were >90% HECs, verified by staining with mouse anti-rat RECA-1 (Harlan Bioproducts for Science, Indianapolis, IN) and mouse anti-Factor VIII-von Willebrand's Factor (Cedar Lane Laboratories Limited, Hornby, Ontario, Canada) [9].
Factor VIII Binding (staining) of
1) Confidence 0.36 Published 2005 Journal BMC Anesthesiol Section Body Doc Link PMC1090549 Disease Relevance 0.21 Pain Relevance 0.03
Laboratory testing performed to exclude a hypercoaguable state, revealed heterozygosity for the Factor V Leiden mutation/activated protein C resistance and elevated factor VIII levels [3660 IU l(-1) (<1500)].
factor VIII Binding (heterozygosity) of
2) Confidence 0.31 Published 2003 Journal Br J Radiol Section Abstract Doc Link 12893701 Disease Relevance 0.59 Pain Relevance 0.04
Repeated skin biopsies revealed an atypical endovascular cell proliferation with strong reactivity for factor VIII.
factor VIII Binding (reactivity) of in skin
3) Confidence 0.30 Published 2006 Journal Scand. J. Rheumatol. Section Abstract Doc Link 16766373 Disease Relevance 1.18 Pain Relevance 0.22
Factor VIII rebounded more than T0 level at T2 and T3.
Factor VIII Binding (rebounded) of
4) Confidence 0.10 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2876854 Disease Relevance 0 Pain Relevance 0
In the myocardial infarction group, univariate analysis showed that atherothrombotic events were associated with high fibrinogen (p = 0.001), factor VIII:C (p less than 0.001), and von Willebrand factor antigen (vWF:Ag) (p = 0.004) levels and with low high density lipoprotein cholesterol (p = 0.043), factor VII (p = 0.019), and protein C (p = 0.044) levels; multivariate analysis produced associations with high fibrinogen and factor VIII:C levels and low protein C levels.
factor VIII Binding (associations) of associated with myocardial infarction
5) Confidence 0.07 Published 1992 Journal Arterioscler. Thromb. Section Abstract Doc Link 1525121 Disease Relevance 0.95 Pain Relevance 0.17
In the myocardial infarction group, univariate analysis showed that atherothrombotic events were associated with high fibrinogen (p = 0.001), factor VIII:C (p less than 0.001), and von Willebrand factor antigen (vWF:Ag) (p = 0.004) levels and with low high density lipoprotein cholesterol (p = 0.043), factor VII (p = 0.019), and protein C (p = 0.044) levels; multivariate analysis produced associations with high fibrinogen and factor VIII:C levels and low protein C levels.
factor VIII Binding (associated) of associated with myocardial infarction
6) Confidence 0.06 Published 1992 Journal Arterioscler. Thromb. Section Abstract Doc Link 1525121 Disease Relevance 0.76 Pain Relevance 0.16
By both univariate and multivariate analysis, events in the angina pectoris group were associated with high vWF:Ag (p = 0.026) and leukocyte (p = 0.033) levels and the presence of carotid arterial stenosis (p = 0.063); associations with high leukocyte (p = 0.037) and factor VIII:C (p = 0.186) levels, family history (p = 0.031), and diabetes (p = 0.061) were also found in the group with transient ischemic attacks.
factor VIII Binding (associations) of in leukocyte associated with brain hemorrhage, angina, pathologic constriction and diabetes mellitus
7) Confidence 0.06 Published 1992 Journal Arterioscler. Thromb. Section Abstract Doc Link 1525121 Disease Relevance 0.97 Pain Relevance 0.17
A mild to moderate deficiency of factor VIII and von Willebrand factor (vWf) often is associated with gingival bleeding.
factor VIII Binding (associated) of associated with hemorrhage
8) Confidence 0.03 Published 1999 Journal J. Periodontol. Section Abstract Doc Link 10368060 Disease Relevance 0.53 Pain Relevance 0.12
[The factor VIII complex in atherosclerosis].
factor VIII Binding (complex) of associated with increased venous pressure under development
9) Confidence 0.02 Published 1982 Journal Minerva Med. Section Title Doc Link 6817235 Disease Relevance 1.11 Pain Relevance 0.09
RESULTS: A favorable clinical outcome was obtained through a treatment with factor VIII concentrates containing von Willebrand factor which resulted in complete resolution of the sonographic findings within 3 weeks.
factor VIII Binding (treatment) of
10) Confidence 0.01 Published 2006 Journal Pediatr Emerg Care Section Body Doc Link 16983251 Disease Relevance 0.24 Pain Relevance 0
Hematological tests show: mild anemia with leucocytosis; prolonged PT, PTT and ThT; decreased fibrinogen, factor V, factor XIII, plasminogen and alpha2-antiplasmin levels; increased factor VIII:c, von Willebrand factor, and FDPs/D-dimers levels with normal ATIII and platelets.
factor VIII Binding (anemia) of in platelets associated with anaemia
11) Confidence 0.01 Published 2000 Journal Biochimie Section Abstract Doc Link 11086223 Disease Relevance 0.74 Pain Relevance 0.14

General Comments

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