INT108911

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Context Info
Confidence 0.41
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.81
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (HTR3A) plasma membrane (HTR3A) transmembrane transport (HTR3A)
HTR3A (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 47 100.00 Very High Very High Very High
Serotonin 6 100.00 Very High Very High Very High
Cannabinoid 2 93.44 High High
dopamine receptor 1 91.76 High High
anesthesia 1 80.36 Quite High
corticosteroid 13 72.08 Quite High
dexamethasone 26 66.20 Quite High
Neurotransmitter 5 52.20 Quite High
transdermal 60 50.00 Quite Low
cerebral cortex 1 34.44 Quite Low
Disease Link Frequency Relevance Heat
Vomiting 195 100.00 Very High Very High Very High
Post-operative Nausea 6 100.00 Very High Very High Very High
Adverse Drug Reaction 1 85.60 High High
Anxiety Disorder 1 82.16 Quite High
Pressure Volume 2 Under Development 1 80.72 Quite High
Cancer 9 37.48 Quite Low
Erythema 6 5.00 Very Low Very Low Very Low
Headache 6 5.00 Very Low Very Low Very Low
Intestinal Obstruction 6 5.00 Very Low Very Low Very Low
Constipation 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[Prevention of postoperative nausea and vomiting with highly selective 5-HT3 serotonin receptors antagonists during different types of surgery].
Negative_regulation ([Prevention) of Gene_expression (antagonists) of 5-HT3 associated with post-operative nausea, antagonist, vomiting and serotonin
1) Confidence 0.41 Published 2002 Journal Anesteziol Reanimatol Section Title Doc Link 12611303 Disease Relevance 0.61 Pain Relevance 0.28
Metoclopramide administered in high doses acquires the capacity to block 5HT3 receptors, which improves its efficacy but it has frequent side effects.7,25
Negative_regulation (block) of Gene_expression (receptors) of 5HT3
2) Confidence 0.41 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004574 Disease Relevance 1.20 Pain Relevance 0.32

General Comments

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